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Phenotype frequencies of Rh and Kell Blood Group Systems in Blood Transfusion department of Avicenna Military Hospital, Marrakech, Morocco

Authors:- Hafid Zahid, Anass Yahyaoui, Jean Uwingabiye, Abdelhak El Khazraji, Fayçal Labrini, Rachid Hadef, Nezha Messaoudi

Introduction: The purpose of our study is presenting new national statistics of phenotypic prevalence Rhesus systems (Rh) and Kell using a new sample of blood donors.

Materials and Methods: This study was conducted in the blood transfusion department of the Avicenna military hospital of Marrakech on a sample of 1286 donors collected between 01/01/2015 and 31/12/2015. This is a military population dominated by men (99%), and composed of young people aged from 18 to 45 years. The samples have been collected in EDTA tubes. The tests were performed on gel-card or on opaline plate at the laboratory temperature. Reagents used are monoclonal antibodies from Society Bio-Rad.

Results: Our results shows a clear predominance of the Rh1 (D) positive (89.81%) compared to Rh-1 (d) negative (10.19%). CcDee was the most common phenotype (38.95%) followed by ccDee (18.91%) CCDee, ccDEe, ccdee and CcDEe. The ccDEE, CCDEe and ccdEe phenotypes are the minority phenotypes. For the Kell system, the predominance of Kell-1 subjects was clearly observed at a frequency of 93%. The Rh D allele was the most prevalent (68.08%) among RH blood type alleles while and the Kell-1 (96.44%) was the frequent among the alleles of Kell blood group system.

Discussion and Conclusion: our results compared to previous national and international studies show that Morocco is in an intermediate situation among the Caucasoid and negroids populations.[Full Article]

KEY WORDS: Phenotype, Rhesus typing, Kell system, Blood Donors, Morocco

Published in : International Journal of Medicine and Health Research

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