Background: Natural products have been found to be effective with least side effects as compared to commercially available synthetic treatment options. Medicinal plants produce bioactive molecules which show both antibacterial and antifungal activities. The bark powder ethanol extract and root oil of cinnamon has antimicrobial and anti inflammatory property. Cinnamon has a long history of usage as a medicinal product. Chinese medicines have used cinnamon as a neuro protective agent. It is also known to be used for the treatment of type 2 diabetes mellitus. Since the antibiotic resistance is increasing, and natural products are known to have antimicrobial property, it seemed worthwhile in assessing its efficacy as a mouth rinse. Aim & objective: To assess the antimicrobial property of cinnamomum verum as a mouthrinse compared to 0.12% chlorhexidine gluconate. Materials and methods: 30 participants were selected randomly for the study. They were divided into 3 groups. Pre and post saliva samples were collected before and after the administration of the respective mouth rinse. The microbial count was calculated from the samples. Results. Among the 3 groups chlorhexidine showed better antimicrobial property than crude extract of cinnamomum verum, but crude extract of cinnamon did show a reduction in the microbial count.
A protocol was optimized for the caulogenesis of fiver nut. Internodal explant showed immediate response in shoot regeneration and production of callus in in vitro cultures of Caesalpinia bonducella (L.) Roxb. commonly known as fiver nut. MS medium supplemented with 1 to 10 mg/l GA 3 was found to induce callus. The Internodal explant inoculated on MS medium with 6 mg/l GA3 was found to produce shoots after 35 days of inoculation. Maximum amount of pale yellow coloured friable callus was produced in 7mg/l GA3 of dry weight 1.513± 0.108 g. The method can be used to generate callus and shoot which are natural sources of pharmaceutical Compounds without disturbing the natural population of the plant.