The emergence of extended spectrum beta-lactamases producing enterobacteriaceae (ESBL-E) to antimicrobials is a problem of public health. This study was a descriptive investigation of the intestinal carriage of ESBL-E within pediatric unit of the University Hospital Center Zafisaona Gabriel in Mahajanga. In whole, 46 individuals were enrolled, 37% (n=17) of whom were carriers of ESBL-E. No relation was established either between ESBL-E occurrence and gender, or age or previous admission (p>0,05). However the intake of antibiotics all along the past three months was associated with the ESBL-E carriage (p=0.02), 95%IC [23.0-50.9]. Isolates bacteria detected were Escherichia coli (47%), Klebsiella (41%) and Citrobacter koseri (12%). One out of three children admitted in pediatric unit carried ESBL-E. It reflects how antimicrobial drugs are managed on children.
Groundwater is normally considered a “safe-source” of drinking water as it is usually having a low microbial load that could be consumed without treatment. However, groundwater sources are often vulnerable to contamination, thus lowering their quality. The aim of the study was to examine the water quality in the rural environs of HRBR Layout, Bangalore, India for the presence of enteric bacteria. Twenty random sampling points were selected. The water sample collected from wells of residential homes in the rural environs of HRBR Layout and subjected to physiochemical analysis and bacterial examination. All samples examined showed higher dissolved oxygen values than the limit set by the World Health Organisation [WHO]. The total dissolved solids for the samples ranged from 199.33 ± 2.07 – 819.33 ± 2.01 mg/L while the total suspended solids ranged from 020.67 ± 3.06 – 393.33 ± 5.37 mg/L. According to WHO and Bureau of Indian Standards [BIS] Standards, none of the water samples are safe for drinking based on the MPN index, while according to Central Pollution Control Board [CPCB], the some of the water sample can be utilized (>50 MPN/ 100 ml). The following bacteria were isolated from the water samples: Enterobacter spp., Escherichia spp., Klebsiella spp., Salmonella spp., Shigella spp., and Yersinia spp. It is recommended that the water for domestic use in the study area be subjected to on-site treatment interventions to protect the households and the public from using such water.