Plants and their derivatives played a key role in world health and have long been known to possess biological activity. The importance of biological evaluations of plants derived agents used in the treatment of various diseases. The data of the acute toxicity studies (oral) on medicinal plants obtained in order to increase the confidence in its safety to human, particularly for use in the development of pharmaceuticals. The aim of this work was to study the effects of repeated dosage of two concentration of plant extracts such as 400mg/kg and 600mg/kg were administered to Swiss albino mice daily for 15 days (orally) to check the safety profile of plant extracts. Mice were randomly selected and each group contains three animals, and analyse the physical parameters, biochemical parameters and liver toxicity were studied at the end of the experiment and analyse the histopathological studies to done for 400mg/kg of group animals assess any organ specific toxicity. From the study there was no changes were observed in liver section when compared with treated and control groups. 

 Over the last decades pediatric obesity has become global epidemic with an estimate of 45 million children and adolescent being affected and this is exponentially increasing. Obesity is leading to a significant mortality and morbidity.

 Traditional medicines derived from medicinal plants are used by about 60 per cent world population. Diabetes is an important human ailment officiating many from various walk of life in different countries including India. It providing to a major health problem, especially in the urban area: Gymnema sylvestre R.Br. (Asclepiadaceae) is a herb distributed throughout the world. The leaves of the plant are widely used for the treatment of diabetes and as diuretic in India proprietary medicine. G. sylvestre, an Ayurvedic herb, came to be known as “destroyer of sugar” because, in ancient times, Ayurvedia physicians observed that chewing a few leaves of G. sylvestre suppressed the taste of sugar. It is used totally all over India for controlling blood sugar. Several bio-active compounds have been isolated from the herb for diabetes care. It is believed to be used in dyspepsia, constipation, jaundice, haemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A scrutiny of literature revealed some notable pharmacological activities of the plant such as anti diabetic, antiobesity, hypolipidaemic, antimicrobial, free radical scavenging and anti-inflammatory. The present review is an attempton various ethanobotanical and traditional uses, phytochemical and pharmacological approaches of G. sylvestre . 

 An essential oil is a concentrated hydrophobic liquid containing volatile aroma compounds from plants. Linaloolis a naturally occurring terpene alcohol chemical found in many flowers and spice plants with many commercial applications. In this present study the linalool was isolated from Jasminum polyanthum and its pharmacological activities such as Anti Spasmolytic and Anti inflammatory were analyzed by In vitro method. The Jasminum polyanthum and linolool possesses the anti spasmodic activity. The prevention value of inhibition or stimulation the Jasminum polyanthum and Linolool contains 50% and 65% of Activity. The Jasminum polyanthum shows 47.30% of anti inflammatory activity where as the Linolool shows high activity 70% respectively. From this study the isolated linalool essential oil possess the anti spasmodic activity which can be applied in pharmacy for the treatment of muscle problems and other related problems.

 Vermicomposting technology is one of the best options available for the treatment of organics-rich solid wastes. In which earth worm converts biodegradable garbage into high quality manure and plays a key role in soil biology and they serve as versatile natural bioreactors to harness energy and destroy soil pathogens. The worms feed voraciously on all biodegradable wastes. There is an instance of chemical toxicity among non target organisms like earthworms etc, in agricultural lands due to pollution of chemical companies and factories. In the present investigation vermicomposting ability of earthworms Eudrilus eugeniae were measured experimentally by exposing in moist leaf litter with Aluminium. The morphological changes observed during the exposure of animals were observed in laboratory conditions and appears to impair the different stages of reproductive cycle of the worms thereby resulting in the onset of reduced vermicomposting ability of the earthworm.

 Aluminium compounds are used in pharmaceuticals and in water treatment processes. Exposure to aluminium is inevitable in this modern life. The purpose of this study was to evaluate the possible effects that aluminium chloride could have on the histology of the cerebellum of Wistar rats. Ten Wistar rats were used for this study; and they were divided into two groups. Group I was the control that received distilled water only while group II received 40mg/kg of aluminium chloride for duration of four weeks. After four weeks of administration of aluminium chloride except for the group I that received distilled water only, the Wistar rats were humanly sacrificed and brain tissues removed, fixed in Bouin’s fluid, processed and stain in Haematoxylin and Eosin. The slides were viewed under the light microscope fitted to a digital camera and Laptop. Our observations showed Purkinje cell loss in the aluminium treated group when compared with the control. We therefore conclude that aluminium chloride had neuro-degenerating effects on the cerebellum of Wistar rats as eminent in the Purkinje cell loss.